Removes the designation of subbasins in the list of river basin designations from the "Major River Basins and Sub-basins in North Carolina" map in GS 143-215.22G. Amends subdivision (1b) to combine subbasins within the primary river, i.e. Cape Fear River including Haw River, Deep River, South River, and Northeast Cape Fear River. Applies to water withdrawals or transfers initiated on or after the effective date of the act.

Amends Section 15 of SL 2020-18 (Specify that the TMDL Transport Factor Applies when Offsetting Certain Permitted Wastewater Discharges) to allow the TMDL transport factor exceptions from subsection (a) of that bill to apply to all wastewater discharge permit applications for local governments in the Neuse River basin.