Makes organizational changes to GS 106-121, setting forth the definitions applicable to Article. Adds and defines the terms cosmetic product; intentionally added chemical; manufacturer; nonfunction by-product; nonfunctional contaminant; practical quantification limit; and restricted substance.

Amends GS 106-136, enacting a new subdivision (6) to deem a cosmetic to be adulterated if it contains one of 12 identified restricted substances as an intentionally added chemical in any amount, including as a nonfunctional by-product or a nonfunctional contaminant above the practical quantification limit. Requires the practical quantification limit, as defined, to be based on scientifically defensible, standard analytical methods, and permits varying limits based on analytical method used. Amends GS 106-132 to deem unsafe for any particular use or intended use any added poisonous or added deleterious substance, any food additive, any pesticide chemical in or on a raw agricultural commodity or any color additive with respect to any cosmetic for application of new GS 106-136(6).

Enacts GS 106-141.2, authorizing the Board of Agriculture (Board) to issue a notice requesting a certificate of compliance to the manufacturer of a cosmetic product it has reason to believe contains a restricted substance as an intentionally added chemical and is being offered for sale in violation of the Article. Requires the manufacturer to provide a certificate attesting that the cosmetic does not contain a restricted substance as an intentionally added chemical within 30 days of notice. Requires manufacturers that do not provide a certificate of compliance to (1) notify all persons that sell the cosmetic product in the State that its sale is prohibited, and (2) provide the Board with the list of names and addressed the manufacturer notified within 30 days of the notice.

Effective January 1, 2026.