Contains whereas clauses. Names the act the Youth End Nicotine Dependence Act.

Amends GS 143C-9-3 to add another annual appropriation from the tobacco litigation Settlement Reserve Fund (Fund), in the amount of $17 million to the Tobacco Use Prevention Fund (Prevention Fund) established under GS 143C-9-3.1, discussed below.

Establishes the Prevention Fund as an interest-bearing special fund in the Department of Health and Human Services (DHHS), Division of Public Health, Chronic Disease and Injury Section (Section) to prevent the use of new and emerging tobacco products, including electronic cigarettes, especially among youth and people of childbearing age. Specifies that the Prevention Fund consists of amounts appropriated from the Fund, and that any remaining balances at the end of the fiscal year carry forward for the next succeeding fiscal year. Limits DHHS from expending any money in the Prevention Fund for any uses other than the seven specified, as well as the administrative uses specified, including: (1) funding local health departments through a regional infrastructure to provide community-based education and training of youth leaders, schools, and local agencies regarding Centers for Disease Control and Prevention evidence-based tobacco use prevention and cessation interventions, including interventions addressing e-cigarettes; (2) tracking tobacco use and exposure, including exposure to e-cigarettes and emerging tobacco products, among young people and populations most at risk for tobacco use; and (3) funding evidence-based media and education campaigns on the health risks of tobacco use, including e-cigarettes. Requires DHHS to submit an annual report to the specified NCGA committee and the Fiscal Research Division on expenditures made from the Prevention Fund during the preceding fiscal year by March 1.

Effective July 1, 2025.