Amends GS 115C-12(23) (Powers and duties of the State Board of Education generally) and GS 115C-47(4) (Powers and duties generally of local boards of education) as the title indicates. Enacts new GS 115C-565.1 to provide guidelines governing the eligibility and participation of home-schooled students in interscholastic athletics. Requires a home-schooled student to register the student's intent to participate in interscholastic athletics at the selected school before the beginning date of the season for the activity in which the student wishes to participate. Applies beginning with the 2011-12 school year.