Creates an 18-member Commission as title indicates. Directs the study to consider multiple issues relating to the State prison health care system, including medical tracking systems in use, whether the system would benefit from a centralized governing body, and whether uniform standards would result in increased outcomes and reduced costs. Allows the Commission to report to the General Assembly in an interim report by August 1, 2019, and requires a final report by December 31, 2019.  Terminates Commission the earlier of December 31, 2019, or the filing of its final report.